Parkinson’s disease is a progressive neurodegenerative disorder that leads to the gradual loss of mobility, balance, coordination, and speech. In its early stages, symptoms are often mild but progressively worsen, causing fatigue and cognitive or behavioral changes over time.
Parkinson’s is primarily managed with:
– Levodopa (L-DOPA) or dopamine agonists to replenish or mimic dopamine levels.
– Deep Brain Stimulation (DBS) to regulate abnormal brain activity and improve motor symptoms.
Mesenchymal Stem Cell (MSC) Therapy for Parkinson’s Disease
The potential of Mesenchymal Stromal Cells (MSCs) offers hope for Parkinson’s patients. MSCs, derived from a patient’s bone marrow or expanded fat tissue, can induce anti-inflammatory effects and may be differentiated in laboratory conditions into dopaminergic-like neurons capable of secreting dopamine.
Future therapies could involve targeting these differentiated MSCs to the substantia nigra, replacing damaged dopamine-producing neurons. While still experimental, this approach aims to restore motor control and slow disease progression.
Repetitive Deep Transmagnetic Stimulation (dTMS) at Biotherapy International
Biotherapy International offers an approved alternative treatment for Parkinson’s using repetitive deep transmagnetic stimulation (dTMS). This advanced device, available at our Tel Aviv clinic, is specifically modified to treat the brain, spinal cord, and broader central nervous system. Regulatory authorities in Israel, Europe, and the USA have approved dTMS for Parkinson’s and other neurological conditions.
Combination Therapies
Our working hypothesis suggests that combining dTMS with mesenchymal stem cell therapy could enhance treatment outcomes. Secondary inflammatory reactions often accompany central nervous system damage, and the anti-inflammatory effects of MSCs, combined with the regenerative potential of dTMS, may provide a synergistic approach to managing Parkinson’s disease.
Parkinson’s research is advancing, and with these innovative therapies, there is hope for improving patients’ quality of life and slowing disease progression.
